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Beitragstitel | Reproducibility of peripapillary Blood flow Measurements of the Nidek Laser Speckle Flowgraphy LSFG-NAVI System |
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Beitragscode | P07 |
Autor:innen | |
Präsentationsform | ePoster |
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Abstract-Text |
Purpose Peripapillary blood flow has diagnostic value in glaucoma. We investigated the reproducibility of peripapillary blood flow measurements in healthy individuals and in open angle glaucoma (OAG). Methods Healthy individuals and patients with OAG were recruited for this prospective single centre trial. Spherical equivalent, best-corrected visual acuity (BCVA), mean defect in static perimetry, blood pressure, heart rate, and peripapillary blood flow quantified by the Nidek laser-speckle flowgraphy (LSFG) NAVI system were measured. Blood flow was calculated as the mean of defect vascular area (MV), mean of tissue area (MT), and mean of overall flow (MA). Intra-rater, inter-session, and inter-rater reproducibility were assessed determining intraclass correlation coefficient (ICC) and coefficient of variance (COV). Results Mean age was 29.5 years (min/max 21/63) in the group of healthy eyes and 58.0 years (45/91) in the OAG group. ICC and COV of intra-rater reproducibility were assessed in MV as (0.901; 6.424), MT (0.909; 4.025), MA (0.965; 4.168). Inter-session reproducibility yielded ICC and COV values of MV (0.834; 9.223), MT (0.904; 6.215), MA (0.909; 7.069). Inter-rater reproducibility was computed for MV as 0.78; 9.758, MT 0.890; 7.210, MA 0.888; 6.942. Conclusion High reproducibility of measurements of the peripapillary blood flow with the LSFG system was demonstrated in both groups. |