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Beitragstitel Reproducibility of peripapillary Blood flow Measurements of the Nidek Laser Speckle Flowgraphy LSFG-NAVI System
Beitragscode P07
Autor:innen
  1. Alexander von Vopelius-Feldt University of Zurich
  2. Timothy Hamann UniversitätsSpital Zürich Präsentierende:r
  3. Andreas Mayr University of Bonn
  4. Marc Töteberg-Harms Augusta University
Präsentationsform ePoster
Themengebiete
  • Glaucoma
  • Others
Abstract-Text Purpose
Peripapillary blood flow has diagnostic value in glaucoma. We investigated the reproducibility of peripapillary blood flow measurements in healthy individuals and in open angle glaucoma (OAG).
Methods
Healthy individuals and patients with OAG were recruited for this prospective single centre trial. Spherical equivalent, best-corrected visual acuity (BCVA), mean defect in static perimetry, blood pressure, heart rate, and peripapillary blood flow quantified by the Nidek laser-speckle flowgraphy (LSFG) NAVI system were measured. Blood flow was calculated as the mean of defect vascular area (MV), mean of tissue area (MT), and mean of overall flow (MA). Intra-rater, inter-session, and inter-rater reproducibility were assessed determining intraclass correlation coefficient (ICC) and coefficient of variance (COV).
Results
Mean age was 29.5 years (min/max 21/63) in the group of healthy eyes and 58.0 years (45/91) in the OAG group. ICC and COV of intra-rater reproducibility were assessed in MV as (0.901; 6.424), MT (0.909; 4.025), MA (0.965; 4.168). Inter-session reproducibility yielded ICC and COV values of MV (0.834; 9.223), MT (0.904; 6.215), MA (0.909; 7.069). Inter-rater reproducibility was computed for MV as 0.78; 9.758, MT 0.890; 7.210, MA 0.888; 6.942.
Conclusion
High reproducibility of measurements of the peripapillary blood flow with the LSFG system was demonstrated in both groups.